X-Rays and Nitrogen Mustard
نویسندگان
چکیده
منابع مشابه
Evidence for a Transport Carrier of Nitrogen Mustard in Nitrogen Mustard-sensitive and -resistant L5178Y Lymphoblasts1
inhibited by ouabain and 2,4-dinitrophenol. These findings suggest that transport of HN2 is carrier-mediated and is an active process. The Km for resistant cells was higher than that of sensitive cells, suggesting a decreased affinity of the trans port carrier for drug. The Vmax of resistant cells was lower than that of sensitive lymphoblasts, suggesting decreased trans port capacity in resista...
متن کاملRelation of mitotic activity to the effects of x-rays and nitrogen mustard as indicated by the growth of corn seedlings.
Gilman and Philips (8) list several striking similarities between the biological effects of these chemicals and radiation. They report that â€oeActively proliferating cells are selectively vul nerable to the cytotoxic action of the mustards.†• There is general agreement that, in most cases, dividing cells are more sensitive to radiation than resting cells, but recent literature indicates a co...
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Triboluminescence is shown to produce X-rays from the nanoparticles (NPs) that form as the sticky acrylic adhesive of Scotch tape is peeled from the polyethylene (PE) roll in a vacuum. Prior to peeling, atoms in the adhesive are not under electromagnetic (EM) confinement and have full thermal kT energy. But upon peeling, the atoms in NPs that form in the gap between adhesive and PE are under EM...
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By JEANNE C. BATEMAN,* M.D., CALVIN T. KLOPP, M.D., and J. KEITH CROMER, M.D. M ETHYL his (beta-chloroethyl) amine hydrochloride (referred to hereafter as HN2) has been established as an effective agent in the palliative therapy of certain malignant diseases, includ!ing Hodgkin’s dhsease, lymphosarcoma, mycosis fungoides, chronic leukemia, polycythemia and some cases of inoperable carcinoma of ...
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There have been numerous reports as to the clinical results obtained with the chloroethylamines (nitrogen mustards) In the treatment of Hodgkin’s disease, lymphosarcoma and leukemia.’-11’9 There has been a paucity of reported clinical trials in regard to the treatment of bronchogenic carcinoma with nitrogen mustard despite the fact that a few cases of carcinoma of the lung treated with nitrogen...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1969
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(69)86439-8